What are the Benefits of NMN?

What are the Benefits of NMN?


In recent years, Nicotinamide Mononucleotide (NMN) has garnered significant attention in the health and wellness community for its potential benefits. As a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme involved in various cellular processes, NMN has been studied for its potential role in promoting overall health and longevity. In this article, we'll delve into the benefits of NMN supported by scientific research.

Anti-Aging Properties

What are the benefits of NMN?

NMN supplementation like VaraSpan® has been linked to anti-aging effects due to its role in boosting NAD+ levels in cells. NAD+ is crucial for cellular metabolism and energy production. As we age, NAD+ levels decline, leading to cellular dysfunction and age-related health issues. By replenishing NAD+ levels, NMN may support cellular repair mechanisms, potentially slowing down the aging process. (1)

Enhanced Metabolic Function

What are the benefits of NMN?

Research suggests that NMN supplementation may improve metabolic function by enhancing mitochondrial function and promoting efficient energy production. Mitochondria are the powerhouses of the cell responsible for generating energy. NMN supports mitochondrial health by optimizing NAD+ levels, thereby improving metabolism and reducing the risk of metabolic disorders such as obesity and diabetes. (2)

Cognitive Support

What are the benefits of NMN?

NAD+ plays a crucial role in maintaining cognitive function and brain health. Studies have shown that NMN supplementation may help protect against age-related cognitive decline by supporting neuronal repair and improving brain energy metabolism. Additionally, NMN has been linked to enhanced cognitive function, memory retention, and neuroprotection in preclinical studies. (3)

Cardiovascular Health

What are the benefits of NMN?

NMN has shown promising potential in promoting cardiovascular health by supporting vascular function and reducing oxidative stress. By increasing NAD+ levels, NMN may help improve endothelial function, regulate blood pressure, and reduce the risk of cardiovascular diseases such as atherosclerosis and heart failure. Furthermore, NMN's antioxidant properties may protect against oxidative damage to blood vessels, thereby supporting overall cardiovascular function. (4)

Exercise Performance and Recovery

What are the benefits of NMN?

Some research suggests that NMN supplementation may enhance exercise performance and improve recovery by boosting cellular energy production and reducing muscle fatigue. By supporting mitochondrial function and increasing NAD+ levels, NMN may help athletes perform better during workouts and recover faster post-exercise. Additionally, NMN's anti-inflammatory properties may aid in reducing exercise-induced muscle damage and inflammation. (5)


Nicotinamide Mononucleotide (NMN) holds promise as a supplement with various potential health benefits. From its anti-aging properties to its role in supporting metabolic function, cognitive health, cardiovascular health, and exercise performance, NMN continues to be the subject of extensive research. However, it's essential to note that while preliminary studies are promising, more research is needed to fully understand the long-term effects and optimal dosage of NMN supplementation.

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  1. Zhang H, Ryu D, Wu Y, et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016;352(6292):1436-1443.
  2. Mills KF, Yoshida S, Stein LR, et al. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab. 2016;24(6):795-806.
  3. Stein LR, Imai S. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging. EMBO J. 2014;33(12):1321-1340.
  4. de Picciotto NE, Gano LB, Johnson LC, et al. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell. 2016;15(3):522-530.
  5. Uddin GM, Youngson NA, Sinclair DA, Morris MJ. Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice. Front Pharmacol. 2016;7:258.
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