Power of Rightly Dosed Micronutrients: Higher Dosages Aren't Necessarily Better - Varalife®

Power of Rightly Dosed Micronutrients: Higher Dosages Aren't Necessarily Better

In a world where busy schedules often leave us neglecting our nutritional needs, finding convenient yet effective ways to supplement our diets has become paramount. Enter VaraSpan® – a revolutionary 5-in-1 formulation encapsulated for ease and efficiency. This unique blend, contained within V-Fill Capsules, offers the perfect fusion of oil-soluble and water-soluble molecules, providing a comprehensive solution to bridging common nutrient gaps. 

Understanding the Dosage

At the core of VaraSpan® lies a meticulously curated blend of essential micronutrients: 

  • Nicotinamide Mononucleotide (NMN): With 250mg per capsule, VaraSpan® offers a dose optimized for health benefits without the risk of adverse effects associated with higher dosages. While some advocate for higher doses, studies suggest that 250-500mg of NMN daily is sufficient for promoting insulin sensitivity, muscle function, and overall health. 
  • Vegan DHA: Each capsule contains 150mg of Vegan DHA, contributing to cognitive function, heart health, and overall well-being. 
  • Resveratrol: Providing 30mg of Resveratrol, VaraSpan® supports antioxidant activity and cellular health. 
  • Vitamin K2-7: With 27.5mcg of Vitamin K2-7, this formulation aids in bone health and cardiovascular support. 
  • Vitamin D: VaraSpan® includes 300IU of Vitamin D to support immune function and promote bone health. 

Why Not 100% Daily Values? 

While Varalife® acknowledges the importance of meeting daily nutrient requirements, the formulation favors a 'food-first' approach. By offering doses that fill common nutrient gaps, VaraSpan® complements a healthy, varied diet without overwhelming the body with excessive amounts of micronutrients. 

The Importance of Micronutrients in VaraSpan®: 

These five micronutrients were carefully selected for their essential roles in maintaining optimal health. While they can be obtained from various dietary sources, achieving sufficient amounts can be challenging. VaraSpan® bridges this gap by providing a convenient and effective solution backed by extensive research and proven health benefits. 

  1. Precise Dosages for Optimal Health:

VaraSpan®'s formulation begins with a meticulous selection of essential micronutrients, each dosed to perfection to deliver targeted health benefits without overwhelming the body. Take Nicotinamide Mononucleotide (NMN), for instance, which boasts 250mg per capsule—a dosage carefully optimized to harness its health-promoting effects, it’s considered "safe for all" across all age groups.  

Similarly, the inclusion of 150mg Vegan DHA, 30mg Resveratrol, 27.5mcg Vitamin K2-7, and 300IU Vitamin D reflects a commitment to providing doses that fill common nutrient gaps without exceeding recommended daily values. This approach ensures that individuals receive the optimal amount of each micronutrient, supporting overall well-being without unnecessary excess. 

  1. Synergistic Impacts Unveiled:

Beyond individual dosages, VaraSpan®'s true magic lies in its strategic combinations of micronutrients, each carefully selected to enhance the efficacy of the formulation as a whole. For example: 

  • NMN & Resveratrol: The combination of NMN with Resveratrol unlocks synergistic benefits, amplifying the effects of NAD+ supplementation and targeting aging mechanisms more effectively. This strategic pairing showcases VaraSpan®'s commitment to harnessing the power of synergistic interactions for maximum health benefits. 
  • Vitamin D3 & K2-7: By pairing Vitamin D3 with Vitamin K2-7, VaraSpan® optimizes bone and cardiovascular health. The synergy between these two nutrients ensures proper calcium utilization, promoting bone strength and arterial flexibility—a testament to VaraSpan®'s holistic approach to supplementation. 
  1. Innovative Delivery Mechanism:

VaraSpan®'s efficacy is further enhanced by its innovative delivery mechanism—an oil-based formula encapsulated for maximum absorption. By harnessing the solubility of liposoluble compounds like Vitamin D3 and Resveratrol, VaraSpan® ensures superior bioavailability, translating into enhanced effectiveness in supplementation. 

Additionally, the inclusion of Omega-3 alongside Vitamin D3 and K2-7 primes the body for optimal nutrient absorption, further maximizing the synergistic effects within the formulation. This innovative delivery approach underscores VaraSpan®'s commitment to precision and efficacy in promoting optimal health. 

Unlocking the Power of Liposolubility 

Enter Vitamin D3, a liposoluble nutrient that dissolves effortlessly in oil. This inherent property makes an oil-based formula the optimal choice for ensuring maximum absorption in the body. By harnessing the solubility of Vitamin D3 in oil, VaraSpan® paves the way for unparalleled bioavailability, translating into superior effectiveness in supplementation. 

The Synergistic Trio: D3, K2, and Omega-3 

In crafting VaraSpan®, we recognize the synergistic relationship between Vitamin D3 and Vitamin K2. These two essential nutrients complement each other, with Vitamin K2 ensuring proper utilization of calcium facilitated by Vitamin D3. However, to maximize their potential, a conducive environment for absorption is imperative. This is where Omega-3, in its oil format, comes into play. 

The Potential of Omega 3: 

The incorporation of Omega-3 in VaraSpan®'s oil-based formula serves a dual purpose. Not only does it facilitate the absorption of Vitamin D3 and K2, but it also primes the body for optimal resveratrol absorption. As mentioned earlier, resveratrol's efficacy is heightened in the presence of a fat source, making the Omega-3 inclusion pivotal in unlocking its full potential. 

Important notes to consider: Supplement Wisely! 

  1. While Trans-Resveratrol is generally considered safe, high dosages might lead to mild gastrointestinal issues. It is always advisable to consult with a healthcare professional before starting any supplement. 
  2. Studies in animals hint that too much NMN can also have side effects. In humans, probably taking more than 1000 mg per day could lead to an increased risk of side-effects, such as too much reductive stress.
  3. Excessive vitamin D doses don't guarantee better results because the body can only absorb so much. Moderate daily doses of 2,000 to 5,000 IU are usually enough to fix a deficiency and It's better to stick to consistent, lower doses for daily supplementation, as the body can manage them better. Having very high vitamin D levels (>50-60 ng/mL) might actually lead to more harm than good, potentially increasing the risk of falls, fractures, and cancer in older adults, according to some studies. So, while vitamin D is crucial for health, too much isn't necessarily better. 

A Holistic Approach to Supplementation: 

By synergistically combining Vitamin D3, K2, and Omega-3 in an oil format, VaraSpan® sets the stage for comprehensive nutrient absorption. This meticulous formulation not only enhances the bioavailability of individual nutrients but also maximizes the synergistic effects when paired with NMN and resveratrol. The result? A powerhouse supplement that optimizes the benefits of NAD+ supplementation, supporting vitality, longevity, and overall well-being. 

In essence, VaraSpan®'s oil-based formula represents a marriage of science and efficacy, ensuring that each capsule delivers the utmost in nutrient absorption and bioavailability. With VaraSpan®, we invite you to experience the transformative potential of precision supplementation, unlocking a path to optimal health and vitality. 


  1. Zhang, H., Ryu, D., Wu, Y., et al. (2016). NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science, 352(6292), 1436-1443. Retrieved from https://pubmed.ncbi.nlm.nih.gov/27422495/

  2. Gomes, A. P., Price, N. L., Ling, A. J., et al. (2013). Declining NAD⁺ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell, 155(7), 1624-1638. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30213565/

  3. Imai, S. (2016). The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control. NPJ Systems Biology and Applications, 2, 16018. Retrieved from https://pubmed.ncbi.nlm.nih.gov/28835614/

  4. Guarente, L., & Franklin, H. (2012). NAD+ and Sirtuins in Aging and Disease. Cold Spring Harbor perspectives in biology, 4(5), a007415. Retrieved from https://pubmed.ncbi.nlm.nih.gov/28539978/

  5. Booth, S. L. (2013). Vitamin K: Food Composition and Dietary Intakes. Food & Nutrition Research, 57(1), 5505. Retrieved from https://pubmed.ncbi.nlm.nih.gov/23668438/

  6. Bikle, D. D. (2014). Vitamin D Metabolism, Mechanism of Action, and Clinical Applications. Chemistry & Biology, 21(3), 319–329. Retrieved from https://pubmed.ncbi.nlm.nih.gov/31584174/

  7. Manson, J. E., & Bassuk, S. S. (2015). Vitamin D and Prevention of Cancer – Ready for Prime Time? New England Journal of Medicine, 373(16), 1570-1571. Retrieved from https://pubmed.ncbi.nlm.nih.gov/33016609/

  8. Delgado, G. E., Kramer, J. H., & Zeitzer, J. M. (2017). Omega-3 fatty acids and vitamin D in cortical function: An analysis of brightness discrimination. Nutritional Neuroscience, 20(5), 274–280. Retrieved from https://pubmed.ncbi.nlm.nih.gov/28244676/

View All Blogs